Effect of Additional Chromosomal Abnormalities in Acute Promyelocytic Leukemia Treated With All-trans-Retinoic Acid: A Report of 17 Patients
β Scribed by Yasushi Okoshi; Hideki Akiyama; Natsu Kono; Tomoko Matsumura; Daisuke Mizuchi; Shin-Ichiro Mori; Kazuteru Ohashi; Hisashi Sakamaki
- Publisher
- Carden Jennings Publishing
- Year
- 2001
- Tongue
- English
- Weight
- 71 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0925-5710
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We measured N-formyl-methionyl-leucyl-phenylalanine-induced reactive oxygen species production by neutrophils from three patients with acute promyelocytic leukemia during treatment with all-trans retinoic acid using a luminol-enhanced chemiluminescence assay. The maximum level of reactive oxygen spe
We observed a child with acute promyelocytic leukemia (APL) who, at the onset, had extremely severe hemorrhagic and septic complications. According to our experience in Nicaragua, there was avery high risk of early death. The patient was successfully treated with a program that included alltrans ret
## Abstract The use of arsenic trioxide (As~2~O~3~, ATO) combined with allβtrans retinoic acid (ATRA) has recently been reported to induce remission in patients with acute promyelocytic leukemia (APL). However, its efficiency remains inconclusive mainly due to the small number of the available case