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Early diagnosis of ataxia-telangiectasia using radiosensitivity testing

โœ Scribed by Xia Sun; Sara G. Becker-Catania; Helen H. Chun; Mee Jeong Hwang; Yong Huo; Zhijun Wang; Midori Mitui; Ozden Sanal; Luciana Chessa; Barbara Crandall; Richard A. Gatti

Book ID
117848082
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
157 KB
Volume
140
Category
Article
ISSN
1097-6833

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Chromosomal radiosensitivity of ataxia t
Chromosomal radiosensitivity of ataxia telangiectasia cells at different cell cycle stages
โœ A. T. Natarajan; M. Meyers ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Springer ๐ŸŒ English โš– 325 KB

X-ray induced chromosomal aberrations in peripheral blood lymphocytes as well as in skin fibroblasts from ataxia telangiectasia patients, and from normal individuals were studied. At all stages of cell cycles-namely G0, G1, and G2, more aberrations were induced in AT cells than in normal cells. In a