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(E)-5-(2-Bromovinyl)-2′-deoxyuridine (BVDU)

✍ Scribed by Erik De Clercq


Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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(E)-5-(2-bromovinyl)-2′-deoxyuridine (BV
✍ Erik De Clercq 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 291 KB

E)-5-(2-bromovinyl)-2 0 -deoxyuridine (BVDU, Brivudin, Zostex 1 , Zerpex 1 , Zonavir 1 ), now more than 20 years after its discovery, still stands out as a highly potent and selective inhibitor of herpes simplex virus type 1 (HSV-1) and varicella-zoster virus (VZV) infections. It has been used in th