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Dysregulation of cell-cycle-inhibitors p16/MTS1 and p15/MTS2 in pancreatic tumors

Book ID
123594823
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
143 KB
Volume
108
Category
Article
ISSN
0016-5085

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Comparative analysis ofHomo sapiensandMus musculuscyclin-dependent kinase (CDK) inhibitor genes P16 (MTS1) and P15 (MTS2)
โœ Ping Jiang; Steven Stone; Roger Wagner; Susan Wang; Priya Dayananth; Christine A ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 909 KB

Cyclin-dependent kinase inhibitors are a growing family of molecules that regulate important transitions in the cell cycle. At least one of these molecules, p16, has been implicated in human tumorigenesis while its close homolog, p15, is induced by cell contact and transforming growth factor-[3 (TGF