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Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors

✍ Scribed by M Naumann; N Savitskaia; C Eilert; A Schramm; H Kalthoff; W Schmiegel

Book ID
119755351
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
280 KB
Volume
110
Category
Article
ISSN
0016-5085

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✍ Ping Jiang; Steven Stone; Roger Wagner; Susan Wang; Priya Dayananth; Christine A πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 909 KB

Cyclin-dependent kinase inhibitors are a growing family of molecules that regulate important transitions in the cell cycle. At least one of these molecules, p16, has been implicated in human tumorigenesis while its close homolog, p15, is induced by cell contact and transforming growth factor-[3 (TGF