Dynamic Kinetic Resolution of 2-Oxocycloalkanecarbonitriles: Chemoenzymatic Syntheses of Optically Active Cyclic β - and γ -Amino Alcohols
✍ Scribed by Dehli, Juan R.; Gotor, Vicente
- Book ID
- 118130634
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 71 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
Chemoenzymatic dynamic kinetic resolution of b-hydroxy nitriles 1 has been carried out using Candida antarctica lipase B and a ruthenium catalyst. The use of a hydrogen source to depress ketone formation in the dynamic kinetic resolution yields the corresponding acetates 2 in good yield and high ena
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