Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia
β Scribed by Van Vlierberghe, Pieter; Graux, Carlos; Cauwelier, Barbara; Lambert, Frederic; Mentens, Nicole; Beverloo, H Berna; Pieters, Rob; Speleman, Frank; Lahortiga, Idoya; De Keersmaecker, Kim
- Book ID
- 109919548
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 163 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/ng2025
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## Abstract Tβcell acute lymphoblastic leukemia (TβALL) is the result of multiple oncogenic insults of thymocytes. Recently, new __ABL1__ fusion genes have been identified that provide proliferation and survival advantage to lymphoblasts. These are the __NUP214βABL1__ fusion gene, on amplified epis