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PHF6 mutations in T-cell acute lymphoblastic leukemia

✍ Scribed by Van Vlierberghe, Pieter; Palomero, Teresa; Khiabanian, Hossein; Van der Meulen, Joni; Castillo, Mireia; Van Roy, Nadine; De Moerloose, Barbara; Philippé, Jan; González-García, Sara; Toribio, María L

Book ID
109914579
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
569 KB
Volume
42
Category
Article
ISSN
1061-4036

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## Abstract T‐cell acute lymphoblastic leukemia (T‐ALL) is the result of multiple oncogenic insults of thymocytes. Recently, new __ABL1__ fusion genes have been identified that provide proliferation and survival advantage to lymphoblasts. These are the __NUP214‐ABL1__ fusion gene, on amplified epis