Dose-response studies of quazepam
β Scribed by Kales, Anthony; Scharf, Martin B; Bixler, Edward O; Schweitzer, Paula K; Jacoby, Judith A; Soldates, Constantin R
- Book ID
- 109843056
- Publisher
- Nature Publishing Group
- Year
- 1981
- Tongue
- English
- Weight
- 523 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0009-9236
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π SIMILAR VOLUMES
Dose response' refers to the regression of a response on a stimulus. We review a number of options for doseresponse designs, and compare various designs which may be used in practice. We start with two group designs. Next, we introduce basic optimal approximate design theory for simple linear and qu
## Abstract A doubleβblind single oral dose study in 10 healthy volunteers was performed during the day to compare the diurnal effects of quazepam (15 mg) and triazolam (0.25 mg) on psychomotor performance. The central effect of the two benzodiazepines was assessed by means of a computer analysis o
T IS A well established principle that tumor I formation is influenced by the concentration, duration of application, and the amount in which a carcinogen is applied. Studies with tobacco smoke condensate showed that tumor formation was dependent upon the total amount of condensate received rather t