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Dose-response for mutagen-induced mutations to 6-thioguanine resistance in Chinese hamster ovary cells

✍ Scribed by A.W. Hsie; P.A. Brimer; T.J. Mitchell; D.G. Gosslee

Book ID
119091572
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
135 KB
Volume
31
Category
Article
ISSN
0165-1161

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Temporal sequence of mutation for 6-thio
Temporal sequence of mutation for 6-thioguanine resistance in synchronised Chinese hamster cells
✍ I. RaskΓ³; K. Burg; L. Dallmann πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 656 KB

The temporal sequence of mutation to 6-thioguanine resistance was studied in Chinese hamster ovary cells synchronised in S phase. The number of resistant mutants induced following exposure to pulses of bromodeoxyuridine and subsequent selection was significantly greater if BUdR pulses were administe