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Dose-dependent pharmacokinetics of enprofylline and its renal handling in rats

✍ Scribed by Masayuki Nadai; Takaaki Hasegawa; Isao Muraoka; Kenzo Takagi; Toshitaka Nabeshima

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
528 KB
Volume
80
Category
Article
ISSN
0022-3549

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## Abstract The pharmacokinetics of furosemide were investigated in the rat at doses of 10 and 40mg kg^βˆ’1^ corresponding to doses of 80 and 320 mg given to humans based on body surface area. A three‐compartment open model with renal excretion taking place from the shallow peripheral compartment gav