## Abstract The pharmacokinetics of furosemide were investigated in the rat at doses of 10 and 40mg kg^β1^ corresponding to doses of 80 and 320 mg given to humans based on body surface area. A threeβcompartment open model with renal excretion taking place from the shallow peripheral compartment gav
Dose-dependent pharmacokinetics of probenecid in the rat
β Scribed by B-M. Emanuelsson; L. K. Paalzow
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 570 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0142-2782
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π SIMILAR VOLUMES
Flurbiprofen is a chiral 2-arylpropionate used clinically as a racemate. Previously a significant pharmacokinetic interaction between the enantiomers of flurbiprofen has been reported in both rats and humans. The possible mechanism for this interaction was believed to involve competitive protein bin
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