𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dose-dependent kinetics of orally administered 6-mercaptopurine in children with leukemia

✍ Scribed by Yasuhisa Kato; Takeji Matsushita; Kan Chiba; Nobuko Hijiya; Tomomasa Yokoyama; Takashi Ishizaki

Book ID
117162489
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
563 KB
Volume
119
Category
Article
ISSN
1097-6833

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Unusual skin rash following withdrawal o
Unusual skin rash following withdrawal of oral 6-mercaptopurine in children with leukemia
✍ Kirk, Judy A. ;Rogers, Maureen ;Menser, Margaret A. ;Bergin, Mary ;Dalla-Pozza, πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 319 KB

Sixteen episodes of a distinctive, papular rash occurred in eight patients following withdrawal of 6-mercaptopurine (6MP) and methotrexate (MTX) used as maintenance therapy for acute lymphoblastic leukemia (ALL). The rash also developed in one of the eight patients when only 6MP was discontinued. Th

Disposition of oral methotrexate in chil
Disposition of oral methotrexate in children with acute lymphoblastic leukemia and its relation to 6-mercaptopurine pharmacokinetics
✍ Koren, Gideon ;Solh, Hassan ;Klein, Julia ;Soldin, Stephen J. ;Greenberg, Mark πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 444 KB

We studied the disposition phannacokinetics of methotrexate (MTX) given orally to 16 children with acute lyrnphoblastic leukemia (ALL) and its relation to the pharrnacokinetics of 6-mercaptopurine (6MP) in the same children. There was an eightfold variability in area-under-concentration tirnecurve (