𝔖 Bobbio Scriptorium
✦   LIBER   ✦

6-Mercaptopurine in cerebrospinal fluid during oral maintenance therapy of children with acute lymphoblastic leukemia

✍ Scribed by Salah Hayder; Pierre Lafolie; Olle Björk; Lars Åhström; Curt Peterson

Book ID
112963227
Publisher
Springer US
Year
1988
Tongue
English
Weight
219 KB
Volume
5
Category
Article
ISSN
1357-0560

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Intraindividual variation in 6-mercaptop
Intraindividual variation in 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute lymphoblastic leukaemia
✍ P. Lafolie; S. Hayder; O. Björk; C. Peterson 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 318 KB

Intraindividual variation in 6-mercaptopurine (6-MP) kinetics has been little studied. It has now been examined in 18 children with acute lymphoblastic leukaemia (ALL). On 2 to 4 occasions in each patient drug concentrations in plasma and red cells were followed for 4 h after administration by means

Disposition of oral methotrexate in chil
Disposition of oral methotrexate in children with acute lymphoblastic leukemia and its relation to 6-mercaptopurine pharmacokinetics
✍ Koren, Gideon ;Solh, Hassan ;Klein, Julia ;Soldin, Stephen J. ;Greenberg, Mark 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 444 KB

We studied the disposition phannacokinetics of methotrexate (MTX) given orally to 16 children with acute lyrnphoblastic leukemia (ALL) and its relation to the pharrnacokinetics of 6-mercaptopurine (6MP) in the same children. There was an eightfold variability in area-under-concentration tirnecurve (