Brain region binding of the D2/3 agonist
β
Ariel Graff-Guerrero; Matthaeus Willeit; Nathalie Ginovart; David Mamo; Romina M
π
Article
π
2008
π
John Wiley and Sons
π
English
β 412 KB
## Abstract The D~2~ receptors exist in either the highβ or lowβaffinity state with respect to agonists, and while agonists bind preferentially to the highβaffinity state, antagonists do not distinguish between the two states. [^11^C]β(+)βPHNO is a PET D~2~ __agonist__ radioligand and therefore pro