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Synthesis of [methoxy-3H]- and [methoxy-11C]- labelled raclopride. Specific dopamine-D2 receptor ligands

✍ Scribed by Erling Ehrin; Lars Gawell; Thomas Högberg; Tomas de Paulis; Peter Ström


Publisher
John Wiley and Sons
Year
1987
Tongue
French
Weight
381 KB
Volume
24
Category
Article
ISSN
0022-2135

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Synthesis of [carbonyl-14C]- and (methox
✍ Kazuharu Tamazawa; Hideki Arima 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 485 KB

## Abstract A new potent neuroleptic agent YM‐09151‐2, N‐[(2RS, 3RS)‐1‐benzyl‐2‐methyl‐3‐pyrrolidinyl]‐5‐chloro‐2‐methoxy‐4‐ (methylamino) benzamide (**10c**), was labeled with carbon‐14 and deuterium for biochemical studies such as metabolism and 14 pharmacokinetics. The synthesis of [carbonyl‐^14