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Radiosynthesis and ex vivo evaluation of (−)-2-Chloro-N-[11C]propyl-Norapomorphine, a novel dopamine D2 receptor agonist

✍ Scribed by Mikael Palner; P. McCormick; N. Gillings; A.A. Wilson; G.M. Knudsen; M. Begtrup


Book ID
118491072
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
69 KB
Volume
41
Category
Article
ISSN
1053-8119

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Radiosynthesis and in vivo evaluation of
✍ Frédéric Dollé; Héric Valette; Stéphane Demphel; Christine Coulon; Michelle Otta 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 193 KB

## Abstract [2‐(3,4‐Dihydro‐1H‐isoquinolin‐2‐yl)‐pyridin‐4‐yl]‐dimethylamine, Ro‐647312 (**1**) represents a new novel class of NR1/2B subtype selective NMDA ligand. Ro‐647312 has been radiolabelled with carbon‐11 using [^11^C]methyl triflate from the __nor‐__methyl compound **2**. The reaction was