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Dominant lethal mutations induced by14C in mice

✍ Scribed by S. N. Goud; O. S. Reddi; P. P. Reddy

Publisher
Springer
Year
1981
Tongue
English
Weight
215 KB
Volume
37
Category
Article
ISSN
1420-682X

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Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal