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Dominant cataract mutations induced by γ-irradiation of male mice

✍ Scribed by Jana Kratochvilova; U.H. Ehling


Book ID
113191622
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
177 KB
Volume
63
Category
Article
ISSN
0027-5107

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Induction of dominant lethal mutations i
✍ U. H. Ehling 📂 Article 📅 1978 🏛 Springer-Verlag 🌐 English ⚖ 342 KB

Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal