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DNA strand breaks in murine lymphocytes: Induction by purine and pyrimidine analogues

✍ Scribed by Wenda L. Greer; J.G. Kaplan

Book ID
117056237
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
306 KB
Volume
115
Category
Article
ISSN
0006-291X

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In vitro exposure of normal human diploid fibroblasts (strain VH-10) to ethylene oxide (EtO) induced DNA strand breaks in the dose range of 2.5-30 mMh of EtO. Alkaline DNA unwinding (ADU), neutral filter elution (NFE), pulsed field gel electrophoresis (PFGE), and the comet assay were used to measure