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Induction of dna strand breaks by genotoxicants in the alga Chlamydomonas reinhardtii

✍ Scribed by Rhiannon M. David; Matthew J. Winter; J. Kevin Chipman

Book ID
111849159
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
431 KB
Volume
28
Category
Article
ISSN
0730-7268

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In vitro exposure of normal human diploid fibroblasts (strain VH-10) to ethylene oxide (EtO) induced DNA strand breaks in the dose range of 2.5-30 mMh of EtO. Alkaline DNA unwinding (ADU), neutral filter elution (NFE), pulsed field gel electrophoresis (PFGE), and the comet assay were used to measure