Formation of DNA strand breaks by D-penicillamine and bucillamine in human lymphocytes
β Scribed by Hisashi Yamanaka; Masayuki Hakoda; Naoyuki Kamatani; Sadao Kashiwazaki; Dennis A. Carson
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 370 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0162-3109
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Methylglyoxal (MG) , a dietary mutagen, is present in various frequently consumed beverages and foods and in cigarette smoke. A combination of S, nuclease hydrolysis and alkaline unwinding assay was used to demonstrate the formation of single-strand breaks and interstrand cross-links in DNA upon tr
In vitro exposure of normal human diploid fibroblasts (strain VH-10) to ethylene oxide (EtO) induced DNA strand breaks in the dose range of 2.5-30 mMh of EtO. Alkaline DNA unwinding (ADU), neutral filter elution (NFE), pulsed field gel electrophoresis (PFGE), and the comet assay were used to measure