✦ LIBER ✦

DNA repair in E. coli strains deficient in single-strand DNA binding protein

✍ Scribed by Whittier, Robert F. ;Chase, John W.

Publisher: Springer
Year: 1981
Tongue: English
Weight: 765 KB
Volume: 183
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00270638

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✦ Synopsis

Weigle reactivation and mutagenesis have been found to be defective in strains of E. coli deficient in single-strand DNA binding protein (SSB). These defects parallel those previously found in prophage induction and amplification of recA protein synthesis in ssb- strains. Together, these results demonstrate a role for SSB in the induction of SOS responses. UV survival studies of ssb- recA- and ssb- uvr- strains are presented which also suggest a role for SSB in recombinational repair processes but not in excision repair. Studies of host cell reactivation support this latter conclusion.

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