✦ LIBER ✦

Role of the E. coli umuC gene product in the repair of single-stranded DNA phage

✍ Scribed by Defais, M.

Publisher: Springer
Year: 1983
Tongue: English
Weight: 291 KB
Volume: 192
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00392198

No coin nor oath required. For personal study only.

✦ Synopsis

The umuC product of Escherichia coli has been suggested to have a central role in SOS induced error prone replication of DNA (Kato and Shinoura 1977). To investigate this possibility, we examined the effect of umuC mutations on error prone repair of single and double-stranded DNA phages. No Weigle reactivation of M13 phage was detected in a umuC mutant. Reactivation of lambda phage was reduced but still evident. However mutagenesis occurred in both cases. These results suggest that induced error prone replication of phage DNA can occur via umuC dependent (transdimer synthesis) and umuC independent mechanisms.

📜 SIMILAR VOLUMES

The role of E. coli single-stranded DNA

The role of E. coli single-stranded DNA binding protein in DNA metabolism

✍ John W. Chase 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 612 KB

## Single-stranded DNA binding proteins have been known for some time to be crucial in many D N A metabolic reactions in both prokaryotes and eukaryotes. Despite a wealth of studies on these proteins we still do not understand their biochemical mechanism of action. Recent studies of the Escherichi

Host genes involved in the replication o

Host genes involved in the replication of single-stranded DNA phage ϕK

✍ Taketo, Akira 📂 Article 📅 1976 🏛 Springer 🌐 English ⚖ 491 KB

Using various replication mutants of E. coli, the host genes that participate in the replication of some K12-specific single-stranded DNA phages have been determined. Functional products of dnaE, -F, -G and -Z genes are required for the multiplication of phiK, whereas dnaA, -B, -C(D), H, -I and -P a

Growth and reactivation of single strand

Growth and reactivation of single stranded DNA phage?X174 in E. coli undergoing ?thymineless death?

✍ Thakur, Ashoke R. ;Poddar, Ramendra K. 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 476 KB

The thymine requirement of the E. coli strain HF 4704 (uvr A-, rec A+) is thermosensitive i.e. these cells require for their growth 2 microng thymine per ml at 37 degrees C but not at 30 degrees C. Such cells when starved for thymine for 3 h at 37 degrees C are capable of sustaining growth of single

The role of umuC gene product in mutagen

The role of umuC gene product in mutagenesis by simple alkylating agents

✍ Schendel, Paul F. ;Defais, Martine 📂 Article 📅 1980 🏛 Springer 🌐 English ⚖ 452 KB

Involvement in DNA repair of the ruvA ge

Involvement in DNA repair of the ruvA gene of Escherichia coli

✍ Iwasaki, Hiroshi ;Shiba, Toshikazu ;Nakata, Atsuo ;Shinagawa, Hideo 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 427 KB

Role of the RecF gene product in UV muta

Role of the RecF gene product in UV mutagenesis of lambda phage

✍ Wood, Richard Dean ;Stein, Judith 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 341 KB

E. coli recF mutants have a greatly reduced capacity for Weigle mutagenesis of ultraviolet light-irradiated lambda phage. A recF 332::Tn3 mutation was introduced into an E. coli recA441 lexA51 strain which constitutively expresses SOS functions. Weigle mutagenesis of phage lambda could occur in the