Translesion DNA synthesis polymerases in
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The Vinh Ho; Orlando D. SchΓ€rer
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Article
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2010
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John Wiley and Sons
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English
β 560 KB
## Abstract DNA interstrand crosslinks (ICLs) are induced by a number of bifunctional antitumor drugs such as cisplatin, mitomycin C, or the nitrogen mustards as well as endogenous agents formed by lipid peroxidation. The repair of ICLs requires the coordinated interplay of a number of genome maint