Eukaryotic DNA polymerases in DNA replication and DNA repair
β Scribed by Peter M. J. Burgers
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 283 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0009-5915
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
One of the fundamental characteristics of life is the ability of an entity to reproduce itself, which stems from the ability of the DNA molecule to replicate itself. The initiation step of DNA replication, where control over the timing and frequency of replication is exerted, is poorly understood in
## Abstract DNA interstrand crosslinks (ICLs) are induced by a number of bifunctional antitumor drugs such as cisplatin, mitomycin C, or the nitrogen mustards as well as endogenous agents formed by lipid peroxidation. The repair of ICLs requires the coordinated interplay of a number of genome maint
## Abstract During the past few years significant progress has been made in our understanding of the structure and function of the proteins involved in eukaryotic DNA replication. Data from several laboratories suggest that, in contrast to prokaryotic DNA replication, two distinct DNA polymerases a