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DNA polymerase activity in a repair-deficient human cell line

โœ Scribed by C.O. Joe; J.O. Norman; T.R. Irvin; D.L. Busbee

Book ID
115758201
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
383 KB
Volume
128
Category
Article
ISSN
0006-291X

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Human tumor cells, after x-irradiation during the G2 phase of the cell cycle, show an abnormally high frequency of persistent chromatid breaks and gaps resulting from deficient DNA repair. Addition of a single human chromosome 11 from normal fibroblasts by micro-cell fusion to cell lines from six di