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DNA Mutation Detection in a Polymer Microfluidic Network Using Temperature Gradient Gel Electrophoresis

✍ Scribed by Buch, Jesse S.; Kimball, Christopher; Rosenberger, Frederick; Highsmith,, W. Edward; DeVoe, Don L.; Lee, Cheng S.


Book ID
111690916
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
134 KB
Volume
76
Category
Article
ISSN
0003-2700

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## Communicated by Johannes Zschocke A method for mutation detection in the alpha-1 antitrypsin gene (protease inhibitor 1; PI) has been developed using denaturing gradient gel electrophoresis of PCR amplified gene fragments. Using this experimental approach, all common phenotypes and mutations co