We report the set-up of a denaturant gradient gel electrophoresis (DGGE) assay to screen for mutations in the whole coding sequence of the p53 gene. These DGGE experimental conditions were applied to the analysis of the p53 gene in acute leukemias. Forty adults with acute myelogenous leukemia (AML)
β¦ LIBER β¦
Selecting DNA fragments for mutation detection by temperature gradient gel electrophoresis: Application to the p53 gene cDNA
β Scribed by Song-Hua Ke; Patrick J. Kelly; Dr. Roger M. Wartell; Stephen Hunter; Vijay A. Varma
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 577 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0173-0835
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