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DNA adducts in mouse and rat epidermis dermis after topical application of (±)-7β,8α,-dihydroxy-9α,10α,-epoxy-7, 8,9,10- tetrahydrobenzo(a)pyrene and (±) benzo(a)pyrene- 4.5-oxide

✍ Scribed by Rojas, M.; Alexandrov, K.


Book ID
123415932
Publisher
Elsevier Science
Year
1987
Weight
119 KB
Volume
23
Category
Article
ISSN
0277-5379

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The reaction of (±)-7α, 8β-dihydroxy-9β,
✍ M. R. Osborne; P. Brookes; F. A. Beland; R. G. Harvey 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 539 KB

## Abstract The reaction of (±)‐7α,8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(__a__)pyrene (BP diol epoxide) with DNA, followed by enzymatic hydrolysis and LH 20 Sephadex column chromatography, yielded products containing a purine deoxyribonucleoside linked to a 7,8,9,10‐tetrahydrobenzo(__a