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Distribution of 1-(3H)methyl-4-phenyl-1,2,3,6-tetrahydropyridine (3H-MPTP) in the Frog: Uptake in Neuromelanin

✍ Scribed by Sokolowski, Annika Lydén ;Larsson, Bengt S. ;Lindquist, Nils Gunnar


Book ID
114801428
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
810 KB
Volume
66
Category
Article
ISSN
0901-9928

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## Abstract In 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) models of Parkinson's disease (PD), dopaminergic (DA) neurons have been shown to die by apoptosis. Moreover, recent postmortem and in vitro results have indicated that apoptotic cell death induced by 1‐methyl‐4‐phenylpyridinium (MPP