Distribution and excretion of [14C]polychlorinated biphenyls after their prolonged administration to male rats
β Scribed by K. Hashimoto; S. Akasaka; Y. Takagi; M. Kataoka; T. Otake; Y. Murata; S. Aburada; T. Kitaura; H. Uda
- Book ID
- 119002342
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 578 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0041-008X
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Meglumine labeled with carbon-14 was administered orally as 14C-meglumine salicylate to rats and dogs to study its distribution and excretion. The compound was incompletely absorbed; that which was absorbed was rapidly excreted in the urine. Peak blood levels were about 5-10 mug/ml in rats and 2-8 m
## Abstract Rats were injected with 120 ΞΌCi of ^14^Cβacetaldehyde containing carrier acetaldehyde, and the urinary excretion products were assayed by cation exchange chromatography, resolving five main peaks of radioactivity. Urine contained 6% of the dose of ^14^Cβacetaldehyde administered. The ma