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Absorption, tissue distribution and excretion of radiolabelled compounds in rats after administration of [14C]-l-α-glycerylphosphorylcholine

✍ Scribed by G. Abbiati; T. Fossati; G. Lachmann; M. Bergamaschi; C. Castiglioni


Book ID
113005968
Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
729 KB
Volume
18
Category
Article
ISSN
0378-7966

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✍ Joel F. Heeg; Gordon S. Born; Wayne V. Kessler; Stanley M. Shaw; Winthrop E. Lan 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 526 KB

Meglumine labeled with carbon-14 was administered orally as 14C-meglumine salicylate to rats and dogs to study its distribution and excretion. The compound was incompletely absorbed; that which was absorbed was rapidly excreted in the urine. Peak blood levels were about 5-10 mug/ml in rats and 2-8 m