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ABSORPTION, METABOLISM AND DISTRIBUTION OF [14C]-O-METHYLDOPA AND [14C]-l-DOPA AFTER ORAL ADMINISTRATION TO RATS

✍ Scribed by LEONOR RIVERA-CALIMLIM

Book ID
117956505
Publisher
Nature Publishing Group
Year
1974
Tongue
English
Weight
537 KB
Volume
50
Category
Article
ISSN
0007-1188

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Absorption, distribution and excretion o
Absorption, distribution and excretion of 14C-meglumine in rats and dogs after administration of 14C-meglumine salicylate
✍ Joel F. Heeg; Gordon S. Born; Wayne V. Kessler; Stanley M. Shaw; Winthrop E. Lan πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 526 KB

Meglumine labeled with carbon-14 was administered orally as 14C-meglumine salicylate to rats and dogs to study its distribution and excretion. The compound was incompletely absorbed; that which was absorbed was rapidly excreted in the urine. Peak blood levels were about 5-10 mug/ml in rats and 2-8 m