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Dissimilar actions of 6-mercaptopurine and 6-thioguanine in Chinese hamster ovary cells

โœ Scribed by Jonathan Maybaum; Laura A. Hink; W.Maurice Roethel; H.George Mande


Book ID
115778167
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
637 KB
Volume
34
Category
Article
ISSN
0006-2952

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Cytotoxicity and mutagenicity of 6-amino
โœ F. Sanz; J. M. Pozuelo; A. Santa Maria ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 340 KB ๐Ÿ‘ 2 views

A strong teratogen-6-aminonicotinamide (6-AN)-was tested for its ability to induce cytotoxicity and mutagenicity in Chinese hamster ovary (CHO) cells. Tests were performed in the presence and absence of a metabolic activation system (S-9 mix). Cytotoxicity was evaluated in CHO cells by the total pro