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Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome

✍ Scribed by Weksberg, Rosanna; Ren Shen, Ding; Ling Fei, Yan; Li Song, Qian; Squire, Jeremy


Book ID
109918216
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
742 KB
Volume
5
Category
Article
ISSN
1061-4036

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Paternal allele-specific expression is identified for the insulinlike growth factor 2 (IGFZ) gene. Relaxation or loss of IGFZ imprinting, however, has been reported in several neoplasms. We studied the expression of IGFZ mRNA in 35 s q w m w s cancers of the esophagus and searched for the presence