✦ LIBER ✦

Discovery of LY314582 and its (+) enantiomer, LY354740: Highly potent and selective group 2 metabotropic glutamate receptor agonists

✍ Scribed by J.A. Monn; M.J. Valli; R.A. Wright; B.G. Johnson; C.R. Salhoff; N.G. Mayne; J.P. Burnett; D.R. Helton; M.J. Kallman; J.P. Tizzano; D.D. Schoepp

Book ID: 116037974
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 132 KB
Volume: 35
Category: Article
ISSN: 0028-3908
DOI: 10.1016/0028-3908(96)84728-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stereocontrolled synthesis of a potent a

Stereocontrolled synthesis of a potent agonist of group II metabotropic glutamate receptors, (+)-LY354740, and its related derivatives

✍ Yasufumi Ohfune; Takashi Demura; Seiji Iwama; Hiromi Matsuda; Kosuke Namba; Keik 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 258 KB

Efficient synthesis of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740: 1) and its structurally related analogs (-)-2 and (-)-3 has been accomplished starting with (1S,2R)-1-amino-2-hydroxycyclopentane-or cyclohexanecarboxylic acid (4 or 17 ) via an intramolecular cyclopropanation of

Stereocontrolled Synthesis of a Potent A

Stereocontrolled Synthesis of a Potent Agonist of Group II Metabotropic Glutamate Receptors, (+)-LY354740, and Its Related Derivatives.

✍ Yasufumi Ohfune; Takashi Demura; Seiji Iwama; Hiromi Matsuda; Kosuke Namba; Keik 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 72 KB 👁 2 views

Asymmetric synthesis of LY354740: A high

Asymmetric synthesis of LY354740: A highly potent and selective group 2 mGluR agonist

✍ Carmen Domínguez; Jesús Ezquerra; Modesta Espada; Carmen Pedregal; Lourdes Priet 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 126 KB

Presynaptic inhibitory action of the gro

Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV

✍ John Kilbride; LingQian Huang; Michael J. Rowan; Roger Anwyl 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 608 KB

Potent, stereoselective, and brain regio

Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist

✍ D. D. Schoepp; Bryan G. Johnson; Rebecca A. Wright; Craig R. Salhoff; James A. M 📂 Article 📅 1998 🏛 Springer-Verlag 🌐 English ⚖ 102 KB

LY341495 is a nanomolar potent and selec

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

✍ A.E Kingston; P.L Ornstein; R.A Wright; B.G Johnson; N.G Mayne; J.P Burnett; R B 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 379 KB