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Discovery of Brivanib Alaninate (( S )-(( R )-1-(4-(4-Fluoro-2-methyl-1 H -indol-5-yloxy)-5-methylpyrrolo[2,1- f ][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), A Novel Prodrug of Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinase Inhibitor (BMS-540215)

✍ Scribed by Cai, Zhen-wei; Zhang, Yongzheng; Borzilleri, Robert M.; Qian, Ligang; Barbosa, Stephanie; Wei, Donna; Zheng, Xiaoping; Wu, Lawrence; Fan, Junying; Shi, Zhongping; Wautlet, Barri S.; Mortillo, Steve; Jeyaseelan, Robert; Kukral, Daniel W.; Kamath, Amrita; Marathe, Punit; D’Arienzo, Celia; Derbin, George; Barrish, Joel C.; Robl, Jeffrey A.; Hunt, John T.; Lombardo, Louis J.; Fargnoli, Joseph; Bhide, Rajeev S.

Book ID: 119943666
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 243 KB
Volume: 51
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm7013309

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