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Discovery and Preclinical Studies of ( R )-1-(4-(4-Fluoro-2-methyl-1 H -indol-5-yloxy)-5- methylpyrrolo[2,1- f ][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an In Vivo Active Potent VEGFR-2 Inhibitor

✍ Scribed by Bhide, Rajeev S.; Cai, Zhen-Wei; Zhang, Yong-Zheng; Qian, Ligang; Wei, Donna; Barbosa, Stephanie; Lombardo, Louis J.; Borzilleri, Robert M.; Zheng, Xiaoping; Wu, Laurence I.; Barrish, Joel C.; Kim, Soong-Hoon; Leavitt, Kenneth; Mathur, Arvind; Leith, Leslie; Chao, Sam; Wautlet, Barri; Mortillo, Steven; Jeyaseelan, Robert; Kukral, Daniel; Hunt, John T.; Kamath, Amrita; Fura, Aberra; Vyas, Viral; Marathe, Punit; D'Arienzo, Celia; Derbin, George; Fargnoli, Joseph

Book ID: 120041305
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 77 KB
Volume: 49
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm051106d

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