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Discovery of N -(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

✍ Scribed by Lombardo, Louis J.; Lee, Francis Y.; Chen, Ping; Norris, Derek; Barrish, Joel C.; Behnia, Kamelia; Castaneda, Stephen; Cornelius, Lyndon A. M.; Das, Jagabandhu; Doweyko, Arthur M.; Fairchild, Craig; Hunt, John T.; Inigo, Ivan; Johnston, Kathy; Kamath, Amrita; Kan, David; Klei, Herbert; Marathe, Punit; Pang, Suhong; Peterson, Russell; Pitt, Sidney; Schieven, Gary L.; Schmidt, Robert J.; Tokarski, John; Wen, Mei-Li; Wityak, John; Borzilleri, Robert M.

Book ID: 120514534
Publisher: American Chemical Society
Year: 2004
Tongue: English
Weight: 307 KB
Volume: 47
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm049486a

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