2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan-Src Kinase Inhibitor

✍ Scribed by Das, Jagabandhu; Chen, Ping; Norris, Derek; Padmanabha, Ramesh; Lin, James; Moquin, Robert V.; Shen, Zhongqi; Cook, Lynda S.; Doweyko, Arthur M.; Pitt, Sidney

• Book ID: 115449072
• Publisher: American Chemical Society
• Year: 2006
• Tongue: English
• Weight: 396 KB
• Volume: 49
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm060727j