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Direct measurement of octanol-water partition coefficients by high-pressure liquid chromatography

✍ Scribed by Mirrlees, Margaret S.; Moulton, Stuart J; Murphy, Christopher T.; Taylor, Peter J.

Book ID
120457375
Publisher
American Chemical Society
Year
1976
Tongue
English
Weight
692 KB
Volume
19
Category
Article
ISSN
0022-2623

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The use of liquid chromatography to estimate octanol-water partition coefficients, log k,,, has been demonstrated. The capacity factor with a mobile phase of 100% water, k,, has been found to be a useful chromatographic parameter. Values of k, were derived from a computer software package (Hipac-G),