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Predicting 1-octanol-water partition coefficient by high-performance liquid chromatography gradient elution

✍ Scribed by A. Kaune; M. Knorrenschild; A. Kettrup

Book ID
112291226
Publisher
Springer
Year
1995
Tongue
English
Weight
877 KB
Volume
352
Category
Article
ISSN
1618-2650

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Determination of octanol-water partition
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The use of liquid chromatography to estimate octanol-water partition coefficients, log k,,, has been demonstrated. The capacity factor with a mobile phase of 100% water, k,, has been found to be a useful chromatographic parameter. Values of k, were derived from a computer software package (Hipac-G),