Determination of Octanol/Water Partition Coefficients of Certain Organophosphorus Compounds Using High-Performance Liquid Chromatography
β Scribed by Krikorian, S. Edward ;Chorn, Trevor A. ;King, James W.
- Book ID
- 112185231
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 501 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1611-020X
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π SIMILAR VOLUMES
The use of liquid chromatography to estimate octanol-water partition coefficients, log k,,, has been demonstrated. The capacity factor with a mobile phase of 100% water, k,, has been found to be a useful chromatographic parameter. Values of k, were derived from a computer software package (Hipac-G),
Retention times ( R t ) for acrylates, methacrylates, and vinyl monomers were measured with two different columns (CIS Corasil and C8 LiChrosorb) using reverse-phase HPLC in order to obtain their partition coefficients between 1-octanol and water (log P ) . The log P values of test compounds were de