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Differential Regulation of Protease Activated Receptor-1 and Tissue Plasminogen Activator Expression by Shear Stress in Vascular Smooth Muscle Cells

โœ Scribed by Papadaki, M.; Ruef, J.; Nguyen, K. T.; Li, F.; Patterson, C.; Eskin, S. G.; McIntire, L. V.; Runge, M. S.


Book ID
118249643
Publisher
Lippincott Williams and Wilkins
Year
1998
Tongue
English
Weight
404 KB
Volume
83
Category
Article
ISSN
0009-7330

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## Abstract Increased expression of plasminogen activator inhibitor type 1 (PAIโ€1) is associated with decreased apoptosis of neoplastic cells. We sought to determine whether PAIโ€1 alters apoptosis in vascular smooth muscle cells (VSMC) and, if so, by what mechanisms. A twofold increase in the expre