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PS238. Regulation of Endothelin-1 and Endothelin Receptors by Shear Stress in Vascular Smooth Muscle Cells

✍ Scribed by Johan Ekstrand; Anton Razuvaev; Joy Roy; Ulf Hedin

Book ID
119315909
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
165 KB
Volume
51
Category
Article
ISSN
1097-6809

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Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of thi