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Hemodynamic shear stress and cytoskeletal changes regulate endothelin-1 production in vascular endothelial cells

โœ Scribed by Toshisuke Morita; Hiroki Kurihara; Koji Maemura; Ryozo Nagai; Yoshio Yazaki


Book ID
115983795
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
82 KB
Volume
24
Category
Article
ISSN
0022-2828

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Vascular endothelial cells are potent modulators of vascular tone in response to shear stress. Levels of vasoactive peptides such as adrenomedullin (AM), endothelin-1 (ET-1), C-type natriuretic peptide (CNP), and nitric oxide (NO) are affected by fluid shear stress. AM, a potent vasodilator and supp