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Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours

โœ Scribed by Lantuejoul, S; Soria, J C; Moro-Sibilot, D; Morat, L; Veyrenc, S; Lorimier, P; Brichon, P Y; Sabatier, L; Brambilla, C; Brambilla, E


Book ID
109997966
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
367 KB
Volume
90
Category
Article
ISSN
0007-0920

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Loss of heterozygosity and human telomer
โœ Linda Capkova; Marketa Kalinova; Lenka Krskova; Daniela Kodetova; Frantisek Petr ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 249 KB

## Abstract ## BACKGROUND Lung carcinogenesis is a multistep process of accumulation of genetic changes, including loss of heterozygosity (LOH), and precedes phenotypic transformation of the bronchial mucosa. The activity of telomerase, correlating with the hTERT mRNA expression, is detectable in