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Different baseline sister chromatid exchange levels in density fractionated human lymphocytes

โœ Scribed by Berta Santesson

Publisher
Springer
Year
1986
Tongue
English
Weight
613 KB
Volume
73
Category
Article
ISSN
0340-6717

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Variation in the baseline sister chromat
Variation in the baseline sister chromatid exchange frequency in human lymphocytes
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## Abstract The utility of the sister chromatid exchange (SCE) assay for human population studies is potentially limited by the variability associated with individual baseline SCE frequencies. This investigation identifies and quantifies the major sources of preparative and biological variation ass

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Sister chromatid exchange (SCE) in human lymphocytes
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The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giemsa procedure. UV C irradiation promotes SCE dose-dependent in the range of 0-40 mJ/cm2. No difference of this phenomenon may be observed, compairing young volunteers (20-40 year