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Sister chromatid exchange in highly purified human B and T lymphocytes

โœ Scribed by K. Miller


Publisher
Springer
Year
1986
Tongue
English
Weight
438 KB
Volume
72
Category
Article
ISSN
0340-6717

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The number of sister chromatid exchanges (SCE) per metaphase was determined in normal human lymphocytes by the Hoechst-Giemsa procedure. UV C irradiation promotes SCE dose-dependent in the range of 0-40 mJ/cm2. No difference of this phenomenon may be observed, compairing young volunteers (20-40 year

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## Abstract The utility of the sister chromatid exchange (SCE) assay for human population studies is potentially limited by the variability associated with individual baseline SCE frequencies. This investigation identifies and quantifies the major sources of preparative and biological variation ass